Male Fertility

Male Fertility

Male Fertility Diagnosis And Testing

  1. 1
    Age
  2. 2
    Sperm Function
    The ability of a sperm to penetrate a human egg is an important issue.

    Low sperm counts and low motility on the Semen Analysis can often predict whether the sperm that are present are sufficient in numbers and activity to reach the eggs, and then bind to and penetrate them. Other than mixing eggs and sperm in a dish at the time of In Vitro Fertilization (IVF), there is no definitive way to prove that sperm are functioning properly. In rare cases, some men with completely normal Semen Analysis numbers may be found to have sperm that cannot bind to human eggs. Unfortunately, this is usually discovered at IVF.

  3. 3
    Sperm DNA Integrity
    There has been much recent interest in evaluating patients with unexplained infertility, multiple reproductive failure and recurrent miscarriage by evaluating the male’s sperm for DNA fragmentation. These tests are not reliably 100% predictive but may indicate in these rarer cases, whether or not the sperm, rather than the egg, is leading to the fertility problem.
  4. 4
    Sperm Count
    The basic sperm count, achieved by masturbation and examination of the sperm 2-5 days after abstinence is one of the mainstays of making a diagnosis, and should be done even when there is a female factor identified. As many as 40% of couples with fertility problems have issues affecting both partners.
  5. 5
    Genetic
    Men with Klinefelter’s syndrome (47 XXY chromosome makeup instead of 46XY), men with deletions of parts of the Y chromosome, men with balanced translocations, and a few other rarer genetic abnormalities are going to have male infertility.